年6月，国际顶尖医学杂志《BiomedicinePharmacotherapy》发表了一篇关于曲克芦丁药效学研究的文献，展示了曲克芦丁制剂在心内科应用的合理性和广阔的前景：
Abstract(#br)Introduction(#br)Medicinalplantsareincreasinglyusedinthetreatmentofcardiovasculardiseasesduetotheirmultifacetedproperties.Thisstudywasdesignedtoinvestigateanti-arrhythmicandanti-inflammatorypotentialsofthenaturalbioflavonoid,troxerutin(TXR)inmyocardialischemia/reperfusion(I/R)injuryindiabeticrats.(#br)Methods(#br)MaleWistarratswererandomlydividedinto4groups(control,control+TXR[mg/kg,daily],diabetic,anddiabetic+TXR).Type-1diabeteswasinducedbyanintraperitonealinjectionofstreptozotocin(50mg/kg)andlastedfor10weeks.AftermountingontheLangendorffapparatus,isolatedheartsinallgroupsreceivedanormalKrebs–Henseleitsolutionfor20minofstabilizationperiod,followedby30minofregionalischemiathroughligationoftheleftanteriordescendingcoronaryartery,and60minoffullreperfusion.Duringtheexperiment,theelectrocardiogramswererecordedandthearrhythmias[number,durationandincidenceofprematureventricular